Juvéderm® Ultra and Juvéderm® Ultra Plus, approved by the FDA in June 2006, are hyaluronic acid (HA) dermal fillers and the only HA dermal fillers FDA-approved to last one year from initial treatment (includes up to two touch ups), providing a smooth, long-lasting correction of moderate to severe facial wrinkles and folds. Juvéderm® dermal filler is the latest advance in HA dermal filler options from Allergan, Inc.
Juvéderm® is the first and only smooth consistency gel formulation, and the only HA dermal filler developed using the proprietary HYLACROSS™ technology, a technologically advanced manufacturing process that results in a malleable, smooth gel. Juvéderm® flows easily into the skin and creates a smooth, natural look and feel.
All other HA dermal fillers currently on the market have a granular consistency gel. These granules can be seen under 2.4X magnification as opposed to the smooth consistency gel of Juvéderm® dermal filler.
In addition, Juvéderm® contains a high concentration of non-animal, cross-linked HA. This unique attribute provides optimal results with a single treatment in the majority of patients and delivers sustained results for up to one year.
Juvéderm® dermal filler is biodegradable and has demonstrated its safety and effectiveness in patients of color. Studies with Juvéderm® demonstrated no increased risk of hyperpigmentation or hypertrophic scarring in patients of color.
Juvéderm® Ultra and Juvéderm® Ultra Plus can be administered in a smooth-flowing injection, providing physicians with a high level of control for individualized, tailored wrinkle treatment and for achieving a smooth and natural look.
The U.S. Food and Drug Administration (FDA) approved the following formulations of Juvéderm®, providing physicians with the flexibility to tailor each treatment to the particular needs of the patient. Product formulations include:
-Juvéderm® Ultra, a highly cross-linked formulation for more versatility in contouring and volumizing of facial wrinkles and folds
-Juvéderm® Ultra Plus, a more highly cross-linked robust formulation for volumizing and correction of deeper folds and wrinkles
How Juvéderm® works
The key component in Juvéderm®, hyaluronic acid, is a naturally occurring, biodegradable complex sugar found in the human body and in all mammals. Among other things, hyaluronic acid hydrates the skin and adds volume, contributing to the overall appearance of the skin.
The ability of cells to produce hyaluronic acid diminishes with age, often resulting in the formation of facial wrinkles and folds as the skin loses volume. Juvéderm® is administered in small doses by intradermal injection directly into moderate to severe facial wrinkles and folds, such as nasolabial folds (the “parentheses” along the side of the nose and mouth), temporarily filling and augmenting the treated area.
Juvéderm® Ultra and Juvéderm® Ultra Plus should only be administered by a trained and qualified health care provider.